OCTOBER 2, 2019


Thank you for making our meeting a success!



Date: 2 October 2019
Meeting venue: Van Beuningen Zaal (Level 3), De Doelen ICC, Rotterdam, The Netherlands
Enrolment: The meeting is designed for scientist and consultants.

GREC (Gadolinium Research & Education Committee) is joining the ESMRMB as a working group and it is our pleasure to invite you to the first ESMRMB-GREC meeting.

The meeting is designed as unique space aimed at sharing ideas and data on MRI contrast agent research and possible gadolinium toxicity after the administration of gadolinium-based contrast agents (GBCAs). We believe that joint international efforts will remain essential to optimize diagnostic efficacy and improve patient safety in MR imaging.
After the European Medicines Agency (EMA) recommended the suspension of the marketing authorization for high-risk GBCAs, the European landscape has changed significantly. Despite the recognition that linear GBCAs are depositing more gadolinium than macrocyclic GBCAs, no health effects have been associated with either class of agents.
Nevertheless, many knowledge gaps remain. Many of these have been identified during the 2018 ACR/RSNA/NIH international meeting, which has outlined a research agenda for the years ahead. The improvement of knowledge through research remains essential to better determine the long-term effects of GBCA exposure. An update of ongoing gadolinium research will be presented.

We look forward to seeing you in Rotterdam!

Cristina Lavini and Aart van der Molen
Meeting Organisers

Institutional Scientific Patronage provided by ESMRMB, Radiological Society of the Netherlands, and the Dutch Society of Clinical Physics.


  • To present the state of research on gadolinium deposition and potential toxicity
  • To further develop and improve preclinical and clinical GBCA research
  • To understand gadolinium deposition in the body in broader context – chemical properties and forms, deposition in other organs, toxicology
  • To foster scientific collaboration between European and non-European institutions

Preliminary Programme



Welcome and practical meeting issues

Session 1 - New ESMRMB-GREC Committee

09:30 – 09:40 – Introduction of Chairs
09:40 – 09:50 – Outline of ESMRMB-GREC in the years ahead (C. C. Quattrocchi)
09:50 – 10:10 – ESMRMB 2019: Focus on Gadolinium-free Imaging (A. Radbruch)
10:10 – 10:30 – INTERA Project Horizon 2020 (C. C. Quattrocchi)
10:30 – 11:00 – Questions and Discussions

Coffee Break

11:00 – 11:30 Coffee Break

Session 2 - 2019 Update on Gadolinium Research

15 minute lectures + 5 minute questions

11:30 – 11:50 – What is new in Gadolinium chemistry & speciation (S. Aime)
11:50 – 12:10 – What is new in Gadolinium deposition in the braind & body (A. Rovira)
12:10 – 12:30 – State of the art in Gadolinium neurotoxicity in humans, animals and in vitro (C. A. Mallio)
12:30 – 12:40 – Questions and Discussion


12:40 – 13:30 – Lunch Break

Session 3 - Invited Speakers and Proffered Talks, Miscellaneous Topics

13:30 – 14:00 – Update on newest animal data from sheep and rodent experiments (A. Radbruch, U. Karst, A. Jeibmann, H. Richter)
14:00 – 14:20 – Guidelines on Contrast Media in the Netherlands: Safe Use of GBCA 2019 (R. Geenen)
14:20 – 14:40 – Gadolinium contamination of surface water (U. Karst)
14:40 – 15:00 – Reducing diagnostic Gd emissions into the aquatic environment – What can be done? What can you do? (G. Stroomberg)
15:00 – 15:15 – tbd

Tea Break

15:15 – 15:45 Coffee/Tea Break

Session 4 - Round tables and setting up collaborations

15:45 – 16:45

Table 1: “MR strategies to increase SI of low gadolinium concentrations”

Table 2: “New contrast media”

Table 3: “Neurotoxicity”

Table 4: ” Hot topic from the ESMRMB-GREC research agenda”

Session 5 - GREC matters

16:45 – 17:00 – Progress ESMRMB-GREC Research Agenda EU (C. C. Quattrocchi)
17:00 – 17:45 – Discussion on new working rules (A. van der Molen)
17:45 – 18:00 – GREC-ESMRMB Meeting in 2020 (C. C. Quattrocchi)


Registration to the ESMRMB-GREC Meeting 2019 must be made by completing the respective registration form. Registrations without full name, email, complete postal address, date of birth and payment details cannot be processed.

Registration fee for the ESMRMB-GREC Meeting 2019 includes:

  • admittance to all scientific sessions
  • congress documents
  • certificate of attendance
Registration Fee ESMRMB-GREC Meeting
October 2, 2019
 excl. VAT*
Full Fee € 50

* Please note that for the ESMRMB-GREC meeting registration fees no VAT will apply. All prices indicated are excl. VAT.

Terms & Conditions

Click here to read the Terms & Conditions.

Terms of Cancellation

Cancellations of registrations are possible at any time. However, paid registration fees will not be refunded.


Please contact us at for any questions related to the ESMRMB-GREC 2019 meeting registration or by phone at (+43) 1 533 4064 915.

This event is kindly supported by Siemens Healthcare